George Hopkins may refer to:
- George Hopkins (baseball) (1858âÂÂ?), pre-Negro leagues baseball pitcher and second baseman
- George Hopkins (comedian) (1928âÂÂ2011), American comedian and musician
- George Hopkins (footballer) (1901âÂÂ1974), English footballer
- George Hopkins (parachutist), professional parachutist who parachuted without permission onto Devils Tower in 1941 and got stuck there for six days
- George James Hopkins (1896âÂÂ1985), set designer, playwright and production designer
- George Feltham Hopkins (1856âÂÂ1897), politician in South Australia
- George H. Hopkins (1842âÂÂ?), Michigan politician
- George Henry Evans Hopkins (1898âÂÂ1973), English entomologist
- George Washington Hopkins (1804âÂÂ1861), Virginia politician, diplomat, lawyer, judge and teacher
- George W. Hopkins (1844âÂÂ1925), Florida industrialist