The George Guida Sr. House is a historic U.S. home in Tampa, Florida. It is located at 1516 North Renfrew Avenue. On March 29, 2006, it was added to the U.S. National Register of Historic Places.
The two-story 4,500 square foot home was a center of social life in West Tampa. It had a heart shaped drive. Concerns have been raised over maintenance and use of the city owned property.