George Grimes

George Grimes may refer to:

• George Grimes (American football) (1922–1971), NFL football player for the Detroit Lions
• George Grimes (English politician) (1605–1657), member of parliament and Royalist
• George Grimes (Queensland politician) (1835–1910), member of the Queensland Legislative Assembly
• George F. Grimes (1877–1929), businessman and political figure in Newfoundland