George Cowles

George Cowles may refer to:

• George W. Cowles (1823–1901), U.S. Representative from New York
• George A. Cowles (1836–1887), ranching pioneer in San Diego, California
• George Cowles (soldier) (1780–1860), representative in the Connecticut General Assembly
• George R. Cowles, member of the Connecticut House of representatives from Norwalk