Garrett's Island House is a historic home located near Plymouth, Washington County, North Carolina. It was built about 1760, and is a -story, Georgian / Federal style frame dwelling with a gambrel roof. It has a shed roofed front porch and double-shouldered exterior brick chimney. Garrett's Island House is thought to be the oldest extant dwelling in Washington County.
It was listed on the National Register of Historic Places in 2001.