Gaginsky District () is an administrative district (raion), one of the forty in Nizhny Novgorod Oblast, Russia. Municipally, it is incorporated as Gaginsky Municipal District. It is located in the southeast of the oblast. The area of the district is . Its administrative center is the rural locality (a selo) of Gagino. Population: 12,444 (2010 Census); The population of Gagino accounts for 31.3% of the district's total population.
The district was established in 1929.