Gafargaon () is an upazila of Mymensingh District in Mymensingh Division, Bangladesh.
Gafargaon is located at . It has 73,130 households and total area is 401.16 km<sup>2</sup>. Trishal on the north, Nandail in the east, Hossainpur and Pakundia upazilas of Kishoreganj district, Kapasia and Sreepur upazilas of Gazipur district on the south, and Trishal and Bhaluka upazilas on the west. Nearly three sides of the border are surrounded by the River Brahmaputra, with Kalivana to the south and Sutia to the west. Just land on the north.
According to the 2022 Bangladeshi census, Gafargaon Upazila had 118,365 households and a population of 463,253. 10.07% of the population were under 5 years of age. Gafargaon had a literacy rate (age 7 and over) of 72.98%: 73.65% for males and 72.37% for females, and a sex ratio of 92.86 males for 100 females. 80,544 (17.39%) lived in urban areas.
Gafargaon Upazila consists of Gafargaon Municipality and 15 union parishads. The administrative activities of these unions are divided between two police stations (thanas): Gafargaon Thana and Pagla Thana.
The upazila is further subdivided into 202 mauzas and 214 villages. Gafargaon Municipality is organized into 9 wards and 19 mahallas.
Upazila Health Complex: 1
Upazila Health and Family Welfare Center: 16
Number of beds: 50
Family planning
Health and Family Welfare Center: 11
Family planning clinic: 1
The number of fertile couples: 84,833
According to Banglapedia, Kandipara Askar Ali High School, founded in 1906, is a notable secondary school.