Gadsden is a census-designated place in Richland County, South Carolina, United States. The population was 1,632 at the 2010 census. It is part of the Columbia, South Carolina metropolitan area.
The John J. Kaminer House, Magnolia, Oakwood, and Richland Presbyterian Church are listed on the National Register of Historic Places.
Gadsden is located at latitude 33.846 North and longitude 80.766 West. The elevation is above sea level. According to the U.S. Census Bureau, the town has an area of , of which , or 0.06%, is water. The community is located at the intersection of state highways 48 and 769.
As of the 2020 United States census, there were 1,301 people, 546 households, and 425 families residing in the Town.
Richland County School District One operates area public schools. Gadsden Elementary School is in Gadsden. Gadsden is zoned to Gadsden Elementary, Southeast Middle School, and Lower Richland High School.