Francisco Lorenzo (born October 27, 1971) is a Dominican former professional boxer who competed from 2000 to 2014. He challenged for the WBC super featherweight title in 2008, and originally won the WBC interim title that year, but was not awarded the title due to the controversy of his win over Humberto Soto.
In June 2005, Francisco upset future WBA World, IBF and WBA Lightweight champion Nate Campbell.
On December 20, 2008 Lorenzo lost his second fight with Humberto Soto by twelve round decision, the bout was for the Interim WBC Super Featherweight championship.
Lorenzo opened a gym in the Dominican Repuvblic after retirement. In order to buy equipment for his gym, he got work on a construction company. In 2019, he suffered an accident while working for the construction company and had three fingers from his left hand amputated.