Francesco Antonio Santorio (died 1589) was a Roman Catholic prelate who served as Archbishop of Acerenza e Matera (1586âÂÂ1589) and Archbishop of Santa Severina (1573âÂÂ1586).
On 9 January 1573, Francesco Antonio Santorio was appointed during the papacy of Pope Gregory XIII as Archbishop of Santa Severina. In March 1573, he was consecrated bishop by Giulio Antonio Santorio, Cardinal-Priest of San Bartolomeo all'Isola. On 28 July 1586, he was appointed during the papacy of Pope Sixtus V as Archbishop of Acerenza e Matera. He served as Archbishop of Acerenza e Matera until his death in 1589.