Fluorosulfonyl isocyanate is an organic chemical compound with the molecular formula .
Fluorosulfonyl isocyanate can be made in a reaction of sulfonyl bisisocyanate and fluorosulfonic acid:
It is also formed in an exchange of halogens in chlorosulfonyl isocyanate using sodium monofluoride:
The compound forms a colorless, volatile liquid.
It is soluble in aprotic organic solvents.
The compound is a highly reactive, versatile chemical used in synthesizing polymers, agrochemicals, and advanced materials, notably acting as a linker in click chemistry for drug discovery.