Fluoroacetyl chloride is an acyl chloride.
In 1948, William E. Truce of Purdue University described a synthesis of fluoroacetyl chloride which was undertaken "because of its potential value for introducing the group, âÂÂCOCH<sub>2</sub>F, into organic molecules." In this synthesis, he reacted sodium fluoroacetate with phosphorus pentachloride to obtain the desired compound.