Florentino Ameghino Partido is a partido in the northwest of Buenos Aires Province in Argentina.
The provincial subdivision has a population of about 8,000 inhabitants in an area of , and its capital city is Florentino Ameghino, which is from Buenos Aires.
Florentino Ameghino Partido is named after Argentine naturalist, paleontologist, anthropologist and zoologist Florentino Ameghino.