Filippo Benedetto de Sio (30 November 1585 – 16 August 1651) was a Roman Catholic prelate who served as Bishop of Boiano (1641âÂÂ1651) and Bishop of Caiazzo (1623âÂÂ1641).
Filippo Benedetto de Sio was born in Cava, Italy and ordained a priest in the Order of Friars Minor Conventual. On 8 December 1623, he was appointed by Pope Urban VIII as Bishop of Caiazzo. On 31 December 1623, he was consecrated bishop by Denis-Simon de Marquemont, Archbishop of Lyon, with François Boyvin de Péricard, Bishop of Evreux, and Girolamo Tantucci, Bishop of Grosseto as co-consecrators. On 21 October 1641, he was appointed by Pope Urban VIII as Bishop of Boiano. He served as Bishop of Boiano until his death on 16 August 1651.