Fermignano (Romagnol: Fermignèn) is a comune (municipality) in the Province of Pesaro e Urbino in the Italian region Marche, located about west of Ancona and about southwest of Pesaro.
Renaissance architect Donato Bramante (1444-1514) was born here.
Fermignano's history can be traced to 200 BC, with the name probably deriving from someone named Firmidio. The city grew up around a bridge over the Metauro river. Over the centuries, Fermignano was under the jurisdiction of the Duchy of Urbino. From 1607, it was given its own administrative council.