Fatima Karume (born 15 June 1969) is a Tanzanian lawyer and activist who served as the president of Tanganyika Law Society (TLS) from 2018 to 2019. She succeeded her predecessor, Tundu Lissu, who led the society from 2017 to 2018.
Fatma Karume was born in 1969 into the family of Karume, one of East Africa's most influential political dynasties. Her grandfather, Abeid Amani Karume, was a leader of the Zanzibar Revolution and served as the first President of Zanzibar from 1964 until his assassination in 1972. Her father, Amani Abeid Karume, also served as the President of Zanzibar for two terms from 2000 to 2010.