Eyioma "Enyi" Uwazurike ( ; born May 6, 1998) is an American professional football defensive end for the Denver Broncos of the National Football League (NFL). He played college football for the Iowa State Cyclones.
Uwazurike grew up in Detroit, Michigan and attended Southfield-Lathrup High School.
Uwazurike redshirted his true freshman season due to academics. He became a starter during his redshirt freshman season and had 27 tackles, 5.0 tackles for loss, and one sack. In his first full season as a starter, Uwazurike recorded 32 tackles, 5.5 tackles for loss, and 1.5 sacks and was named honorable mention All-Big 12 Conference. He was again named honorable mention All-Big 12 as a redshirt senior after finishing the season with 27 tackles, eight tackles, and three sacks. Uwazurike decided to utilize the extra year of eligibility granted to college athletes who played in the 2020 season due to the coronavirus pandemic and return to Iowa State for a sixth season. He was named first-team in his final season after finishing the year with 43 tackles, 12 tackles for loss, and nine sacks.
Uwazurike was selected by the Denver Broncos in the fourth round (116th overall) of the 2022 NFL draft, a pick the Broncos received from the Russell Wilson trade.
On July 24, 2023, Uwazurike was suspended indefinitely for gambling violations.
Uwazurike was reinstated by the NFL on August 5, 2024. After playing intermittently during the 2024 season, Uwazurike saw an increased role in 2025 as a rotational defensive lineman.
Uwazurike's family originates from the Biafra region of Nigeria.