Examples of in vitro transdifferentiation by initial epigenetic activation phase approach

List:

• Human dermal fibroblasts → multilineage blood progenitors (Oct4 and cytokine treatment)
• Mouse dermal fibroblasts → polygonal hyaline chondrogenic cells (Klf4, c-Myc, Sox9)
• Mouse dermal fibroblasts → cardiomyocytes (Oct4, Sox2, Klf4, JI1 and Bmp4)
• Fibroblasts → neural stem/progenitor cells (Oct4, Sox2, c-Myc, Klf4)

See also

• Transdifferentiation
• Induced stem cells

References