European route E 641 is a secondary E-road in Austria and Germany.
It starts at Wörgl, Austria, where it is connected with European route E 45 and E 60 (Austrian autobahn A12).
The route then enters Austria again, ending in Salzburg, where it is connected with E 52, E 55 and E 60.
European route E 641 is long, with about in Germany, and in Austria.