Euphorbia longituberculosa is a species of flowering plant in the family Euphorbiaceae, endemic to the Arabian Peninsula and North-east Africa. It inhabits rocky terrain, sheltered among stones or under small shrubs; from sea level to .
Euphorbia longituberculosa has a height of with a tapering root. The stem grows to a height of 8 cm with a thickness of 4 cm which is tuberculate. E. longituberculosa has linear-lanceolate leaves of with similar bracts but smaller.