Euphorbia grandidens, commonly known as valleybush euphorbia or large-toothed euphorbia, is a species of plant in the family Euphorbiaceae native to southern Africa. While sometimes shrubby, it can also be a pachycaulous tree up to tall, with the short horizontal branches in a rosette at the top of the main trunk and reiterations. These horizontal branches are succulent and triangular in cross-section.