Euphorbia acanthothamnos, is a species of flowering plant, belonging to the family Euphorbiaceae.
It is a shrub that reaches 30 cm in height. It forms a thorny cushion that blooms from March to June. It grows mainly in limestone areas.
It is endemic to the eastern Mediterranean, Crete, Greece, and Turkey. It grows from sea level to more than 2000 meters.
Euphorbia acanthothamnos was described by Heldr. & Sart. ex Boiss. and published in Diagnoses Plantarum Orientalium Novarum, ser. 2, 4: 1859. 86.
Acanthothamnos is an epithet that means "thorny bush" in Greek.