Etocyanozene (etocyanazene, 5-cyano-etodesnitazene) is a benzimidazole opioid 'desnitazene' derivative with opioid effects. It was first developed in the 1950s as part of the research that led to better-known compounds such as etonitazene. It is an analogue of etonitazene where the 5-nitro (NO<sub>2</sub>) group has been replaced by a nitrile (Câ¡N) group. It is described as having "reduced but still significant" potency compared to etonitazene itself. It was made illegal in Germany in July 2021.