Etienne Oosthuizen (born 22 December 1992) is a South African rugby union footballer. His regular playing position is either lock or flanker. He represents the in the URC and in the EPCR Challenge Cup.
In September 2012, he signed a contract to join the on a two-year deal. However, he was released from his contract after just one year and returned to South Africa to join the on a two-year contract.
In 2023, Oosthuizen signed a two-year contract with the Johannesburg-based , 11 years after starting his career at the same union.