Esine (Camunian: ) is a comune in the province of Brescia, in the Italian region Lombardy, in the Camonica valley, located north of Brescia.
It is bounded by other communes of Berzo Inferiore, Bovegno, Cividate Camuno, Darfo Boario Terme, Gianico, Piancogno.
Esine is twinned with: