The Episcopal Diocese of Central Pennsylvania was one of the dioceses of the Episcopal Church in the United States of America. It was established in 1904 as the Diocese of Harrisburg, separating from the original Diocese of Central Pennsylvania formerly known as the Episcopal Diocese of Bethlehem. It reunited with the Diocese of Bethlehem in 2026 to form the Diocese of the Susquehanna.
The seat of the bishop and home of the diocesan offices was St. Stephen's Episcopal Cathedral at 221 North Front Street in Downtown Harrisburg, Pennsylvania.
In 2024, the diocese reported average Sunday attendance (ASA) of 2,770 persons.
In 1871, the original Diocese of Central Pennsylvania was established. In 1904, the Diocese of Harrisburg split off from the old Diocese of Central Pennsylvania, leaving the remainder to rename itself the Diocese of Bethlehem in 1909. In the 1970s, the name of Central Pennsylvania was re-adopted by the Diocese of Harrisburg. In October 2022, the diocesan conventions of Central Pennsylvania and Bethlehem initiated the process for exploring reunification. On October 19, 2024, the conventions of the two dioceses both voted to unify as the Episcopal Diocese of the Susquehanna, effective January 1, 2026. On the predetermined date, the dioceses reunited to form the Diocese of the Susquehanna.
In the 1880s, the first boys' choir in the diocese was established at Christ Church in Reading, Pennsylvania.
From October 2006 until May 2014, Nathan D. Baxter was the bishop of the diocese. Following Baxter's retirement Robert R. Gepert was named as provisional bishop of the diocese. On 14 March 2015, Audrey Scanlan was elected to become the next bishop of the diocese; she was consecrated in September 2015.