Epalxis is an extinct genus of sea snails, marine gastropod mollusks in the family Turridae, the turrids.
Cossmann stated the type species of Epalxis to be Pleurotoma crenulata <small>Lamarck, 1804</small>; however he used the latter name in the sense of Deshayes (1834). P. crenulata in the sense of Deshayes and Cossmann is in fact Pleurotoma ventricosa <small>Lamarck, 1804</small>. Brebion [1992, Cossmanniana, Hors-série 1] accepted P. ventricosa as the type species of Epalxis, and Tracey et al. (2019) accepted Brebion's type species fixation under Art. 70.3 and 86.1.1 of the Code. However, Art. 70.3 cannot be applied retroactively to Brebion's type species fixation. Tracey et al. should have invoked Art. 70.3 in their own right if they chose to do so. For the time being, this leaves Pleurotoma crenulata <small>Lamarck, 1804</small>, as the type species of Epalxis by OD.
Species within the genus Epalxis include: