In enzymology, an enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) () is an enzyme that catalyzes the chemical reaction
Thus, the two substrates of this enzyme are acyl-[acyl-carrier-protein] and NADP<sup>+</sup>, whereas its 3 products are trans-2,3-dehydroacyl-[acyl-carrier-protein], NADPH, and H<sup>+</sup>.
This enzyme belongs to the family of oxidoreductases, to be specific, those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is acyl-[acyl-carrier-protein]:NADP+ oxidoreductase (A-specific). Other names in common use include acyl-ACP dehydrogenase, enoyl-[acyl carrier protein] (reduced nicotinamide adenine, dinucleotide phosphate) reductase, NADPH 2-enoyl Co A reductase, enoyl-ACp reductase, and enoyl-[acyl-carrier-protein] reductase (NADPH2, A-specific).