El Salvador sent 274 athletes (151 males, 123 females) to the XXIst Central American and Caribbean Games in Mayagüez, Puerto Rico, July 17 - August 1, 2010.
The athletes participated in: Archery (12), Athletics (8), Badminton (2), Beach Volleyball (4), Bowling (9), Boxing (4), Cycling (13), Equestrian (6), Football (soccer) (34), Fencing (22), Gymnastics (8), Handball (28), Judo (11), Karate Do (11), Roller Speed (7), Rowing (12), Sailing (7), Shooting (12), Softball (16), Squash (6), Swimming (5), Table Tennis (8), Taekwondo (8), Tennis (2), Triathlon (1), Weightlifting (9) and Wrestling (9).