Eduardo "Edu" Barrios Manzano (; born September 14, 1955) is a Filipino actor, television presenter, and politician. He hosted the game shows The Weakest Link, Pilipinas, Game KNB?, 1 vs. 100, Asar Talo Lahat Panalo!, and Game 'N Go.
Manzano was born on September 14, 1955, in San Francisco, California, United States to Hispanofilipino parents hails from Visayas.
Manzano studied at St. Paul University Manila and at De La Salle University in Manila. He also played for De La Salle Green Archers' Judo and basketball teams. He was coached by Joaqui Trillo while La Salle still at the NCAA.
Manzano moved to the Philippines to pursue a full-time career with the local film industry. He was president of the actorsâ group Katipunan ng mga Artista ng Pelikulang Pilipino in the 1990s.
He was part of ABS-CBN's roster of contract actors until he took leave to run for Vice President of the Philippines in the 2010 general elections. After losing in the elections, he elected to transition from show business to current affairs programs, and soon after, signed a contract and returned to GMA Network.
In 2010, he hosted the pre-noontime game show Asar Talo Lahat Panalo!.
In 2011, he hosted Family Feud: The Showdown Edition. Manzano later defected to TV5 for a new TV show called Game 'N Go. In 2012, he joined the morning show called Good Morning Club.
In June 2017, Manzano returned to GMA Network to appear in Celebrity Bluff as a Master Bluffer.
In 2018, he returned to ABS-CBN for a role in FPJ's Ang Probinsyano.
Aside from acting and political career, Manzano was once appointed as the executive vice-president of the Philippine Amateur Judo Association, and as an executive board member of the Philippine Olympic Committee.
Manzano entered politics in 1998 when he ran for Vice Mayor of Makati as a Liberal. He garnered a majority of votes in the election, but his proclamation was suspended due to a case filed which alleged that he was not a Filipino citizen because he was born in the United States. The Supreme Court (Mercado v. Manzano) eventually ruled that he was indeed a Filipino citizen, clearing the way for his proclamation as Vice-Mayor. Following a three-year term, he lost his bid for campaign for Mayor of Makati in 2001 to Jejomar Binay.
In February 2004, Manzano became the first chairman of the Optical Media Board (OMB), a government agency tasked with combating optical media piracy. He resigned from the position in August 2009.
Manzano ran as the LakasâÂÂKampi's candidate for Vice-president in the May 2010 election as the running mate of presidential candidate Gilbert Teodoro. He lost again to Makati Mayor Jejomar Binay, placing fifth.
In 2016, Manzano ran for a seat in the Senate, as part of the Partido Galing at Puso coalition of presidential candidate Senator Grace Poe. He lost, finishing 21st overall.
In 2019, Manzano ran for Representative of San Juan under the Pwersa ng Masang Pilipino. However, he was disqualified by the COMELEC due to concerns regarding his citizenship.
In 2022, Manzano supported Leni Robredo's campaign and some of its senatorial slate members, but blasted his former rival Jejomar Binay, who was also a member of the slate, and supported his friend and former running-mate Gilbert Teodoro's senatorial campaign.
In 1980, Manzano married actress Vilma Santos. The marriage lasted until 1982 and produced one son, Luis Manzano, who followed his parents into the entertainment industry as a television host and actor. In 1989, he married actress Maricel Soriano; however, the marriage was annulled in 1991.
Manzano was in a long-term relationship with former model Rina Samson, with whom he has two children: a daughter, Addie, and a son, Enzo. He later had a high-profile relationship with television news anchor Pinky Webb, which ended in 2009 prior to his vice-presidential campaign. Between 2021 and 2023, he was romantically linked to actress Cherry Pie Picache.
In March 2026, Manzano confirmed he is in a relationship with Ann Cuisia, a tech entrepreneur and the founder of a blockchain technology firm.
Outside of his older children, Manzano has a son, Diego Aspiras (born 2004), from a previous relationship with celebrity chef Reggie Aspiras. Diego is a professional footballer who played for the Spanish club Barcelona City FC.