East Branch Verdigre Creek is a -long third-order tributary to Verdigre Creek in Knox County, Nebraska, United States. This stream along with South Branch Verdigre Creek forms Verdigre Creek.
East Branch Verdigre Creek rises on the Elkhorn River divide about 1.5 miles southeast of Royal, Nebraska and then flows north-northwest to join South Branch Verdigre Creek to form Verdigre Creek about 8 miles east-southeast of Venus, Nebraska.
East Branch Verdigre Creek drains of area, receives about 26.2 in/year of precipitation, has a wetness index of 564.29, and is about 5.53% forested.