ESN Vrilissia or ESN Vrilission () is a Handball club that based in Vrilissia in the regional unit of North Athens, Attica. The full name of club is Ekpolitistikos Syllogos Neon Vrilission () that means Cultural Youth Association Vrilissia. The club was founded in 1979 and has won one Greek Championship and two Cups. In September 2011 the group was withdrawn by the first division championship (A1 Ethniki) because of financial difficulties. In current season the club plays in A2 Ethniki (second division).