The E. K. Burnham House is a historic house located in Cape Vincent, Jefferson County, New York.
It is an Italianate style brick residence built in 1870. It has a three-story, three-bay-wide main block with a central belvedere. Also on the property are a garage and two boathouses built in 1919.
It was listed on the National Register of Historic Places on September 27, 1985.