The Dusheti uezd was a county (uezd) of the Tiflis Governorate of the Caucasus Viceroyalty of the Russian Empire, and then of Democratic Republic of Georgia, with its administrative centre in Dushet (present-day Dusheti). The area of the uezd roughly corresponded to the contemporary Mtskheta-Mtianeti region of Georgia.
Following the Russian Revolution, the Dusheti uezd was incorporated into the short-lived Democratic Republic of Georgia.
The subcounties (uchastoks) of the Dusheti uezd in 1913 were as follows:
According to the 1897 Russian Empire census, the Dusheti uezd had a population of 67,719 on , including 35,848 men and 31,871 women. The majority of the population indicated Georgian to be their mother tongue, with a significant Ossetian speaking minority.
According to the 1917 publication of Kavkazskiy kalendar, the Dusheti uezd had a population of 66,430 on , including 32,949 men and 33,481 women, 65,737 of whom were the permanent population, and 693 were temporary residents: