Drillia sinuosa is a species of sea snail, a marine gastropod mollusk in the family Drilliidae.
Drillia sinuosa <small>McLean, J.H. & R. Poorman, 1971</small> is a junior homonym and is a synonym of Drillia macleani <small>Tucker, J.K., 1992</small>
The length of the shell attains 18 mm.
The solid shell has a turreted shape, with a few prominent longitudinal ribs terminating at the periphery, crossed by close, strong striae. The aperture is broadly cut out below, with no proper siphonal canal. The large anal sinus is ascending. The color of the shell is white, or brownish with white ribs, or whitish indistinctly maculated or centrally banded with light brown.
This species occurs in the Atlantic Ocean off St. Helena.