Dr. William Claudius Irby House, also known as the Crowe House, is a historic home located in Laurens, South Carolina.
The Dr. William Claudius Irby House was built about 1890, and is a two-story, frame residence sheathed in weatherboarding with a cross-gable roof with Eastlake style elements. It features include a two-tiered porch on the façade and a single-story porches on the side elevations. Also on the property is a fieldstone outbuilding.
It was added to the National Register of Historic Places in 1986.