Dr. Virgil Cox House is a historic home located at Galax, Virginia, owned by Virgil J. Cox. It was built about 1913, and is a large -story frame dwelling with Queen Anne and Colonial Revival style design elements. It has a complex exterior presentation, complex roof plan, and an equally complex floor plan. The house is sheathed in German siding and features irregular, front-gable projections on the facade and north side; a projection with a polygonal bay on the southwest corner, a gable-roof dormer on the facade; and a small, upper balcony on the facade with attenuated Tuscan columns and pilasters. Also on the property are a contributing boxwood garden and outbuilding.
It was listed on the National Register of Historic Places in 2004.