Dr. George Rigas House is a historic home located at Weirton, Hancock County, West Virginia. It was built in 1936, and is a five-bay, -story wood-frame house with clapboard siding and a side gable roof. It has an eclectic style. It features a gable-roofed portico centered on the main elevation and supported by four Tuscan order columns and two pilasters. The house is associated with Dr. George S. Rigas, a prominent local physician who practiced medicine in Weirton.
It was listed on the National Register of Historic Places in 2004.