Don Bosco Higher Secondary School is a private, English-medium, co-educational school in Irinjalakuda, Kerala, India. It was established in March 1962.
It began as an English-medium and a Malayalam-medium school and the Government sanctioned it as an unaided but recognised school on 6 May 1962. The Malayalam-medium section was discontinued later. A boarding section started on 2 January 1963 was later closed later. In 1987 an indoor stadium was built to commemorate the Silver Jubilee of the Institution. It is affiliated to the Council of Indian School Certificate Examination (CISCE), New Delhi.