Dimitrios Ypsilantis () is a former municipality in Kozani regional unit, West Macedonia, Greece. Since the 2011 local government reform it is part of the municipality Kozani, of which it is a municipal unit. It was named after Demetrios Ypsilantis, a 19th-century leader of the Greek struggle for independence. The municipal unit has an area of 112.071 km<sup>2</sup>. Population 1,392 (2021). The seat of the municipality was in Mavrodendri.