Descabezado Grande (also Cerro Azul or Quizapu) is a stratovolcano located in the Maule Region of central Chile. It is capped by a ice-filled caldera and named for its flat-topped form, as descabezado means "headless" in Spanish. A smaller crater about wide is found in the northeast part of the caldera, and it has active fumaroles.
The volcano is composed of andesite and rhyodacite lava flows along with pyroclastic flow deposits. It has a basal diameter of about and a total volume of about . Along with Cerro Azul, to the south, it lies at the center of a volcanic field.