Deppea is a genus of flowering plants in the family Rubiaceae native to the region from Mexico to Central America, and from Brazil to Argentina.
Deppea are slender shrubs or small trees with oppositely arranged, or rarely whorled leaves.
The chromosome count of Deppea blumenaviensis is 2n = 28.
The genus is named in honor of Ferdinand Deppe (1794-1861), who collected the type species during a botanical expedition to Veracruz, Mexico with C.J.W. Schiede in 1828-1829. It was described by Diederich Franz Leonhard von Schlechtendal and Adelbert von Chamisso in 1830 with Deppea erythrorhiza as the type species. Within the subfamily Dialypetalanthoideae it is placed in the tribe Hamelieae.
It occurs in Argentina, Brazil, Costa Rica, El Salvador, Guatemala, Honduras, Mexico, and Panama. The centre of diversity is in the mountains of Mexico and Guatemala.