Delta Kappa Epsilon Fraternity House is a historic Delta Kappa Epsilon fraternity house located at Greencastle, Indiana. It was designed by noted Indiana architect Robert Frost Daggett and built in 1926.
It is a three-story, seven-bay, Tudor Revival style building faced in Indiana limestone. The building was originally H-shaped, but has been enlarged. It has a hipped roof and three-bay protruding porch on the first floor.
It was listed on the National Register of Historic Places in 1996. It is located in the Eastern Enlargement Historic District.