ô-Cadinol is an organic compound, a sesquiterpenoid alcohol produced by many plants as well as some animals and microorganisms. It is a white crystalline solid, soluble in isopropyl ether and ethanol. It is an epimer of ñ-cadinol.
ô-Cadinol exists in nature as either of two enantiomers distinguished by the prefixes (+)- and (âÂÂ)-. The (+)-isomer was identified by E. Shinozaki in 1922 from the leaves of Torreya nucifera and originally named torreyol. The (âÂÂ)-isomer was isolated in 1951 by Haagen-Smit and others from Pinus albicaulus and first called albicaulol. Its structure was determined in 1970 by Lars Westfelt. Other names were given to ô-cadinol based on its various biological sources before the structures were confirmed, including sesquigoyol for (+)-ô-cadinol and pilgerol for (âÂÂ)-ô-cadinol. Lambertol is thought to be either (+)-ô-cadinol or (âÂÂ)-ô-cadinol. Cedrelanol was originally thought to be identical to (âÂÂ)-ô-cadinol but was later confirmed to have the structure of ÃÂ-cadinol.
ô-Cadinol is produced by the fungus Xylobolus frustulatus as long white needles when grown in malt agar medium. It also occurs in many conifers, and in many other organisms including