Deir ez-Zor District () is a district of the Deir ez-Zor Governorate in northeastern Syria. The administrative centre is the city of Deir ez-Zor. At the 2004 census, the district had a population of 492,434.
The district of Deir ez-Zor is divided into seven subdistricts or nawÃÂḥë (population as of 2004):