De La Salle High School may refer to:
- De La Salle College (Toronto) in Toronto, Ontario, Canada
- De La Salle High School (Concord, California)
- De La Salle Institute, Chicago, Illinois
- De La Salle High School (New Orleans, Louisiana)
- De La Salle Collegiate High School in Warren, Michigan
- DeLaSalle High School in Minneapolis, Minnesota
- De La Salle North Catholic High School in Portland, Oregon
- Colegio De La Salle in Bayamon, Puerto Rico
See also