DeKalb County Courthouse is a historic courthouse located in Maysville, DeKalb County, Missouri. It was designed by George R. Eckel of Eckel & Aldrich and built in 1939. It is a low red brick building with concrete bands and Moderne style details. It consists of a three-story main block with two-story flanking wings. The building measures 110 feet by 55 feet.
It was listed on the National Register of Historic Places in 1998.