David Syme (disambiguation)

David Syme (1827–1908) was a Scottish-Australian newspaper proprietor (The Age).

David Syme may also refer to:

• David Syme (footballer) (born 1997), Scottish footballer for Cowdenbeath, formerly of Kilmarnock and Partick Thistle
• David Syme (pianist) (born 1949), American pianist
• David Syme (referee) (1944–2020), Scottish football referee