David Middleton

David Middleton may refer to:

• David Middleton (mariner) (died 1617), early English merchant of the East India Company
• David Middleton (cricketer) (born 1965), English cricketer
• Dave Middleton (1933–2007), American football wide receiver
• David Middleton Greig (1864–1936), Scottish surgeon
• David Stephen Middleton (born 1961), suspected serial killer known as The Cable Guy
• David Middleton (civil servant), New Zealand chief executive of the Earthquake Commission (1993–2010)