David Grimes

David Grimes may refer to:

• David Grimes (American football) (born 1986), American football wide receiver
• David Grimes (composer) (born 1948), American composer
• David Grimes (physician) (born 1947), American physician and abortion provider
• David Robert Grimes (born 1985), physicist and cancer researcher at the University of Oxford
• David Grimes (meteorologist), Canadian meteorologist
• David Grimes (politician), Alabama state legislator